Search results for "Trans generational"
showing 3 items of 3 documents
A multicentre randomized controlled trial on trans-generational attention deficit/hyperactivity disorder (ADHD) in mothers and children (AIMAC): an e…
2018
Abstract. Objective: We examined predictors and moderators of treatment outcome in mothers and children diagnosed with ADHD in a large multicentre RCT. Method: In total, 144 mother-child dyads with ADHD were randomly assigned to either a maternal ADHD treatment (group psychotherapy and open methylphenidate medication, TG) or to a control treatment (individual counselling without psycho- or pharmacotherapy, CG). After maternal ADHD treatment, parent-child training (PCT) for all mother-child dyads was added. The final analysis set was based on 123 dyads with completed primary outcome assessments (TG: n = 67, CG: n = 56). The primary outcome was the change in each child’s externalizing sympto…
Trans-generational immune priming is constrained by the maternal immune response in an insect.
2012
5 pages; International audience; Immune-challenged vertebrate and invertebrate females can transfer immunity to their off spring. Th is trans-generational immune priming (TGIP) is benefi cial for the off spring if the maternal infection risk persists across generations. However, because immunity is costly, fi tness consequences of TGIP have been found in primed off spring. Furthermore, transferring immunity to off spring may be costly for immune-challenged females who are also carrying the costs of their immune response. A negative relationship between levels of immunity between mothers and off spring might therefore be expected. Consistent with this hypothesis, we show that in the insect, …
Intra- and Trans-Generational Phenotypic Responses of the Greater Wax Moth, Galleria mellonella, to a Low-Nutrition Larval Diet
2020
We investigated the intra- and trans-generational effects of larval diet on immune function, body size and development time of the greater wax moth, Galleria mellonella (Lepidoptera: Pyralidae). We found that moths reared on a diet diluted with cellulose (a low-nutrition diet) were about one-third smaller, had about one-fifth longer development time and exhibited about 10% stronger encapsulation responses as compared with moths reared on the standard diet. The low-nutrition parental diet prolonged the development time of male offspring that were fed the low-nutrition diet by about 4% and the development time of female offspring that were fed the standard diet by about 1%. However, females t…